neoBona GenomeWide

ABOUT THE TEST

Chromosomal abnormalities, like trisomy 21 (Down's syndrome), are present in the 1-2% of the fetuses.

neoBona is a non-invasive prenatal test (NIPT) that detects chromosomal abnormalities in the fetus without any risk to the future baby, providing highly reliable results for the screening of:

• Aneuploidies¹ most common chromosomes (21, 18 y 13)
• Aneuploidies of the sex chromosomes and fetal sex

¹Alteration in the number of copies of a chromosome.

neoBona GenomeWide provides a more complete view of the fetal genome by analyzing los 23 chromosome pairs to expand screening to other rare chromosomal abnormalities² when evaluating the presence of:

• Anomalies in the rest of the autosomes (non sex chromosomes)
• Deletions and partial duplications³, CNVs of size greater than or equal to 7 Mb in all autosomes

²These anomalies could have clinical relevance as they are associated with pregnancy loss., various structural alterations, fetal abnormalities and developmental and/or growth delays of the fetus.
³ Losses or partial gains of chromosomal regions.

Conventional first trimester screening consists of an analysis and an ultrasound, and provides a statistical risk index. neoBona GenomeWide directly analyzes free fetal DNA, which provides greater reliability and a better detection rate, along with fewer false positives.

The sensitivity of conventional screening is 90%, This means that of each 100 fetuses with Down syndrome (trisomy 21), 10 would not be detected (false negatives). The overall sensitivity of neoBona GenomeWide is greater than 99% for Down syndromes, Edwards and Patau (trisomies 21, 18 y 13).

Unlike other prenatal tests, neoBona GenomeWide analyzes free fetal DNA through a technology that allows determining the size of free DNA fragments, improving the reliability of the result.

IS IT RIGHT FOR ME?

neoBona GenomeWide is indicated for the following cases:

• From the 10th week gestation (10 weeks + 0 days)
• It can be done in cases of rassisted production, including IVF with gamete donation
• It is suitable for twin pregnancies
• It is a genetic screening test and as such must be prescribed by a doctor

PRELIMINARY CONSIDERATIONS

• It is necessary to go to a SYNLAB center to take the test
• It is not necessary to go on an empty stomach
• Necessary medical prescription

WHAT IS THE PROCEDURE?

The test requires a blood sample, so You need to go to a SYNLAB center to take the test so follow the next steps!